News

June 10, 2021

New publication in the SCLS

In this study, we develop an osteoarthritic (OA) cartilage model for developing...

June 4, 2021

New publication in the Frontiers in Pharmacology

In this study, our results show that mechanical overloading results in cartilage degradation partially through...

June 4, 2021

New publication in the Biomaterials Science

In this study, we developed a biodegradable and resilient hydrogel for cartilage tissue...

April 29, 2021

New publication in the Stem Cell Research & Therapy

In this study, we show that soft biomaterials support superior adipogenesis of encapsulated hBMSCs in 3D culture, which is partially mediated by the CAV1-YAP axis.  Suppressing CAV1 expression...

April 13, 2021

New publication in the Front. Bioeng. Biotechnol.

In this study, we found that treatment of FOXO4-DRI, a senolytic peptide, removed senescent cells in...

March 1, 2021

Alan Li Selected for ORS 2021 Student Trainee Registration Award

Congratulations to Alan whose application was selected for the Student/Trainee Registration Award for the 2021 ORS meeting! 

February 11, 2021

Lab Selected As an Awardee for Pitt Momentum Funds

The Lin Lab application Discovering drugs to treat osteoarthritis with a knee joint-on-a-chip model has been selected as an awardee for Pitt Momentum Funds...

January 22, 2021

New publication in the FASEB Journal

In this research article, we developed a convenient method to "rejuvenate" old chondrocytes. Autologous chondrocyte...

January 7, 2021

New publication in Tissue Engineering - Models for DMOAD development

In this review article, we summarize the current status in the development of DMOADs will be first presented, with special attention to...

November 6, 2020

New publication in Biomed Mater - Mesenchymal stem cell-derived extracellular matrix (mECM)

In this review article, we first summarize the development and use of mECM as a scaffold for musculoskeletal tissue regeneration and...

October 30, 2020

New publication in Life Science - Role of mitochondria in mediating chondrocyte response to mechanical stimuli

In this review article, we systemically summarize mitochondrial alterations in chondrocytes during OA progression and discuss our recent...

October 16, 2020

Zhong (Alan) Li Awarded Young Investigator Award and the Student and Young Investigator Sections (SYIS) Scientific Excellence Award

In the Tissue Engineering and Regenerative Medicine International Society (TERMIS) – Americas 2019 Annual Meeting held in Orlando, Florida during Dec 2–5, 2019, Dr. Zhong (Alan) Li, a Postdoctoral...

October 16, 2020

Zhong (Alan) Li Placed Third in McGowan's Scientific Retreat Poster Contest

Zhong (Alan) Li placed third in the Pitt McGowan Scientific Retreat Poster Contest: Tissue Engineering for A Multi-Tissue Chip for the Modeling of...

October 16, 2020

Lin lab receives $1.3M from the DoD to Study Osteoarthritis Pain in Microphysiological System

Osteoarthritis (OA) is a common debilitating and painful disease with a high prevalence in the U.S.. Because pain is the most prominent symptom of OA, it is unfortunate that there are no...